Category Archives: Enterobacter

Transient in vivo selection of a constitutively cephalosporin resistant Enterobacter cloacae:DISCUSSION part 3

Perhaps a more likely explanation is that in vivo factors al Iowed some antibiotic sensitive organisms, esfabIished with the inifial infection, to persist in a relatively antibiotic protected site and be cultured from day 6 to 9. Antibiotic protected sites … Continue reading

Transient in vivo selection of a constitutively cephalosporin resistant Enterobacter cloacae:DISCUSSION part 2

There are very strong data to show that the mechanism of resistance in these isolates was Bush class 1 beta-lactamase. The nifrocefin test showed that beta- I actamase was produced. Clavulanic acid did not inhibit the enzyme (Table 1), cefoxitin … Continue reading

Transient in vivo selection of a constitutively cephalosporin resistant Enterobacter cloacae: DISCUSSION part 1

Selection of Gram-negative rods with constitutive Bush class 1 beta-lactamase production has resulted in emergence of resistance on therapy (with labile weak inducer antibiotics — buy antibiotics online) in 14 to 56% of cases, with treatment failure or relapse in … Continue reading

Transient in vivo selection of a constitutively cephalosporin resistant Enterobacter cloacae:MICROBIOLOGY part 2

The results of the inducible beta-lactamase disk approximation test are shown in Figure 1. Figure 1) The inducible beta-lactamase disk approximation test. A Day 1, 2 and 6 to 9 isolates. Imipenem (I) induces beta-lactamase production and thus a zone … Continue reading

Transient in vivo selection of a constitutively cephalosporin resistant Enterobacter cloacae:MICROBIOLOGY part 1

The susceptibilities of the E cloacae isolates in csf are shown in Table 1; the day 3, 4 and 5 isolates were resistant to second- and third-generation cephalosporins and ticarcillin, whereas all other initial and later isolates were susceptible, Each … Continue reading

Transient in vivo selection of a constitutively cephalosporin resistant Enterobacter cloacae: CASE PRESENTATION part 2

The following day the patient looked well, was a febrile, and the skin along the previous shunt tubing appeared normal and nontender. Cefotaxime was continued and genia-micin was added (7.5 mg/kg/day divided every 8 h). Vancomycin was discontinued. Daily csf … Continue reading

Transient in vivo selection of a constitutively cephalosporin resistant Enterobacter cloacae: CASE PRESENTATION part 1

This eight-day-old Caucasian female was seen by the infectious disease consultant for irritability and fever of one day’s duration. She was delivered by cesarean section (for failure to progress) with birth weight 3800 g to a well mother after a … Continue reading

Transient in vivo selection of a constitutively cephalosporin resistant Enterobacter cloacae causing ventriculitis

BACTERIA EXPRESS BUSH CLASS 1 CHROMOSOME MEDiated beta-lactamases in two ways: low ‘basal’ level production (eg, Escherichia coli, Salmonella species and Shigella species) and ‘inducible’ expression. Inducible expression occurs transiently in the presence of an inducer antibiotic (eg, cefoxitin, imipenem) … Continue reading