Category Archives: Heart failure

Relations between adrenergic response and atrial natriuretic factor release (part 2)

PATIENTS AND METHODS In heart failure plasma norepinephrine concentrations are an acceptable representation of sympathetic nervous system activity or tone . Previous studies have indicated that plasma ANF provides important prognostic information and that ANF concentrations are closely related to … Continue reading

Relations between adrenergic response and atrial natriuretic factor release (part 5)

Hemodynamic measurements were taken at rest and at the end of exercise. Pulsed-wave Doppler ultrasonic measurements of ascending aortic blood velocity from the suprasternal approach were taken by a Doppler ultrasound generator. Standard formulas and echocardiographic measurement of aortic cross-sectional … Continue reading

Relations between adrenergic response and atrial natriuretic factor release (part 19)

In the control group the percentage change in ANF concentrations was positively but not significantly related to percentage changes of both arterial blood pressure (diastolic and systolic blood pressure) and heart rate. In contrast, in the CHF group we observed … Continue reading

Relations between adrenergic response and atrial natriuretic factor release (part 18)

In fact, after exercise catecholamine concentrations were markedly increased in both study groups. Our data show a close relation between both arterial and venous blood ANF variation and catecholamine concentrations. According to these results, previous studies in vitro indicate that … Continue reading

Relations between adrenergic response and atrial natriuretic factor release (part 16)

Ebert , using this technique, demonstrated that nonhypotensive infusions of alpha-human ANF (15 ng/min) produce reflex increases in sympathetic nerve activity through a decrease in cardiac preload, with consequent unloading of cardiopulmonary baroreceptors. Similarly, Roach et al investigated the interaction … Continue reading

Relations between adrenergic response and atrial natriuretic factor release (part 15)

Evidence of interactions between ANF and the sympathetic system in healthy humans: In healthy humans, the effects of ANF on the autonomic nervous system reflexes have been studied by assessing its effects on the responses to lower body negative pressure, … Continue reading

Relations between adrenergic response and atrial natriuretic factor release (part 14)

Experimental evidence of interactions between ANF and the sympathetic system: Early experimental studies employing bioassay for ANF suggested that catecholamine might increase the release of ANF in vitro . More recent investigations in which ANF was measured by RIA yielded … Continue reading

Relations between adrenergic response and atrial natriuretic factor release (part 13). DISCUSSION

DISCUSSION ANF and catecholamine in heart failure: The hemodynamic effects of ANF are potentially of great interest for the comprehension of human heart failure pathophysiology. However, the mechanisms involving ANF-induced reduction of stroke volume are unclear. Reduction of blood volume … Continue reading

Relations between adrenergic response and atrial natriuretic factor release (part 12)

Correlations with hemodynamic measurements: In healthy subjects the percentage change in venous blood ANF concentrations showed a positive but not significant relation with percentage change of both arterial blood pressure (diastolic and systolic blood pressure) and heart rate. In contrast, … Continue reading

Relations between adrenergic response and atrial natriuretic factor release (part 11)

Moreover, the same linear regression analysis was performed with the absolute value variations after exercise in both groups (Figure 4), permitting a better statistical evaluation using both systems. In the control group, a positive but not significant relation was found … Continue reading