Category Archives: Obstructive Sleep Apnea

Augmented Resting Sympathetic Activity in Awake Patients With Obstructive Sleep Apnea: Conclusion

We found no correlation between OSA severity and MSA or plasma NE concentration which is in contrast to Eisenberg et al who demonstrated a relationship between disease severity and plasma NE concentrations at rest. The explanation for this discrepancy may … Continue reading

Augmented Resting Sympathetic Activity in Awake Patients With Obstructive Sleep Apnea: Discussion

The present study shows that awake OSA patients have significantly higher resting levels of MSA than normal controls, confirming the result from a previous preliminary report. In addition, we found that arterial and venous plasma levels of NE were increased … Continue reading

Augmented Resting Sympathetic Activity in Awake Patients With Obstructive Sleep Apnea: Results

Five of the 11 patients filled the criteria for hypertension (Table 1). Average BP was 150 ± 7/70 ±3 mm Hg and 168 ±5/99 ±2 mm Hg in normotensive and hypertensive patients, respectively. The heart rate was 73 ± 4/min … Continue reading

Augmented Resting Sympathetic Activity in Awake Patients With Obstructive Sleep Apnea: Other Recordings

The patients were connected to an oximeter via a finger probe (BIOX 3700, Ohmeda). Respiratory movements were monitored via a strain gauge attached to a strap around the chest. Intra-arterial BP was measured via a catheter inserted into the right … Continue reading

Augmented Resting Sympathetic Activity in Awake Patients With Obstructive Sleep Apnea: Polysomnography

All patients were investigated in the clinical sleep laboratory prior to inclusion in the study. During a full nights sleep, oxygen saturation was measured continuously via a finger probe (BIOX 3700, Ohmeda). Nasal and oral airflow were monitored via thermistors … Continue reading

Augmented Resting Sympathetic Activity in Awake Patients With Obstructive Sleep Apnea: Materials and Methods

Obstructive sleep apnea (OSA) has been recognized as a clinical entity for only approximately 20 years. The pathogenesis has remained obscure. Between 1 and 3 percent of the total population is estimated to suffer from OSA, according to conventional criteria. … Continue reading